This clue appeared in the NYT Crossword on Sunday, May 17, 2026 (101 Across). The answer is hidden below until you want it. Sunday puzzles are large (21 by 21) and themed, about as hard as a Wednesday or Thursday.
Answer length: 4 squares
First letter
S _ _ _
First and last letters
S _ _ S
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About the answer
SALS as a word: (pathology) Abbreviation of sporadic amyotrophic lateral sclerosis; (pathology) Alternative form of sALS; Abbreviation of sporadic amyotrophic lateral sclerosis.
SALS has been an answer 3 times in the NYT Crossword and Mini since December 27, 2025.
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