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Molecule that can self-splice (crossword clue)

3 squares · NYT Crossword · January 16, 2026 · The answer stays hidden until you tap it

This clue appeared in the NYT Crossword on Friday, January 16, 2026 (28 Across). The answer is hidden below until you want it. Friday puzzles are themeless and hard, with clues that are vague on purpose.

Answer length: 3 squares

First letter

R _ _

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About the answer

RNA as a word: (biochemistry) Initialism of ribonucleic acid. [(biochemistry) A derivative of DNA having ribose in place of deoxyribose, and uracil in place of thymine; its....

RNA has been an answer 10 times in the NYT Crossword and Mini since December 28, 2025.

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