This clue appeared in the NYT Crossword on Sunday, December 28, 2025 (75 Across). The answer is hidden below until you want it. Sunday puzzles are large (21 by 21) and themed, about as hard as a Wednesday or Thursday.
Answer length: 3 squares
First letter
R _ _
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About the answer
RNA as a word: (biochemistry) Initialism of ribonucleic acid. [(biochemistry) A derivative of DNA having ribose in place of deoxyribose, and uracil in place of thymine; its....
RNA has been an answer 10 times in the NYT Crossword and Mini since December 28, 2025.
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