This clue appeared in the NYT Crossword on Saturday, November 1, 2025 (50 Across). The answer is hidden below until you want it. Saturday puzzles are the hardest of the week and themeless, so clues are often deliberately misleading.
Answer length: 3 squares
First letter
P _ _
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About the answer
PSA as a word: (medicine, immunology) Initialism of prostate-specific antigen. [(medicine) A glycoprotein enzyme secreted by the epithelial cells of the prostate gland and ...; Initialism of public service announcement. [(broadcasting) An advertisement intended to serve the public interest by raising awareness of an issue, affecting....
PSA has been an answer 9 times in the NYT Crossword and Mini since November 1, 2025.
Other clues with the same answer
More clues from this puzzle
- Superlatively absurd (41 Across)
- Disney-owned channel (44 Across)
- Name of eight popes (45 Across)
- Abbr. next to a year on a company sign (46 Across)
- ___ Games (Fortnite company) (51 Across)
- Speculative venture (52 Across)
- Commercial lead-in to -matic, once (53 Across)
- Acquaintance made at day care drop-off, perhaps (55 Across)
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