This clue appeared in the NYT Crossword on Thursday, August 20, 2026 (11 Across). The answer is hidden below until you want it. Thursday puzzles often have a trick, such as a rebus (several letters in one square) or answers that bend the rules.
Answer length: 3 squares
First letter
P _ _
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About the answer
PSA as a word: (medicine, immunology) Initialism of prostate-specific antigen. [(medicine) A glycoprotein enzyme secreted by the epithelial cells of the prostate gland and ...; Initialism of public service announcement. [(broadcasting) An advertisement intended to serve the public interest by raising awareness of an issue, affecting....
PSA has been an answer 9 times in the NYT Crossword and Mini since November 1, 2025.
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