This clue appeared in the NYT Crossword on Friday, December 19, 2025 (49 Down). The answer is hidden below until you want it. Friday puzzles are themeless and hard, with clues that are vague on purpose.
Answer length: 5 squares
First letter
I _ _ _ _
First and last letters
I _ _ _ O
Show the answer
About the answer
INSPO as a word: (slang) Clipping of inspiration. [(physiology, uncountable) The drawing of air into the lungs, accomplished in mammals by elevation of the chest walls and fl....
INSPO has been an answer 4 times in the NYT Crossword and Mini since December 14, 2025.
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