This clue appeared in the NYT Crossword on Friday, January 2, 2026 (21 Across). The answer is hidden below until you want it. Friday puzzles are themeless and hard, with clues that are vague on purpose.
Answer length: 6 squares
First letter
D _ _ _ _ _
First and last letters
D _ _ _ _ S
Show the answer
About the answer
DEFATS as a word: To remove fat from a material, especially by the use of solvents.
DEFATS has been an answer once in the NYT Crossword and Mini puzzles we have on file, which go back to October 23, 2025.
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