This clue appeared in the NYT Crossword on Wednesday, June 24, 2026 (57 Down). The answer is hidden below until you want it. Wednesday sits mid-week in difficulty, with more wordplay than Monday or Tuesday.
How to read this clue
This is a fill-in-the-blank clue: the answer completes the phrase, title or quotation.
Answer length: 4 squares
First letter
P _ _ _
First and last letters
P _ _ A
Show the answer
About the answer
PEPA as a word: Performance Evaluation Process Algebra is a stochastic process algebra designed for modelling computer and communication systems introduced by Jane Hillston ...; a sulfonamide AMPA receptor positive allosteric modulator, which is up to 100 times more potent than aniracetam in vitro.
PEPA has been an answer once in the NYT Crossword and Mini puzzles we have on file, which go back to October 23, 2025.
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