This clue appeared in the NYT Crossword on Monday, December 22, 2025 (12 Down). The answer is hidden below until you want it. Monday puzzles are the easiest of the week, so the clue is likely a plain definition.
How to read this clue
"E.g." means the clue gives an example, and the answer names the group it belongs to.
Answer length: 7 squares
First letter
A _ _ _ _ _ _
First and last letters
A _ _ _ _ _ Y
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About the answer
ALLERGY as a word: (medicine, immunology, loosely) A disorder of the immune system causing adverse reactions to substances (allergens) not harmful to most and marked by the bod...; (medicine, immunology, strictly) Specifically, hypersensitivity of class I in the modern classification thereof: the immunoglobulin E, mediated type.
ALLERGY has been an answer once in the NYT Crossword and Mini puzzles we have on file, which go back to October 23, 2025.
More clues from this puzzle
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