This clue appeared in the NYT Crossword on Saturday, November 14, 2026 (3 Down). The answer is hidden below until you want it. Saturday puzzles are the hardest of the week and themeless, so clues are often deliberately misleading.
Answer length: 4 squares
First letter
A _ _ _
First and last letters
A _ _ A
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About the answer
ATRA as a word: (organic chemistry, pharmacology) Initialism of all-trans retinoic acid. [(organic chemistry, pharmacology) Tretinoin.].
ATRA has been an answer 3 times in the NYT Crossword and Mini since December 3, 2025.
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