This clue appeared in the NYT Crossword on Tuesday, June 2, 2026 (44 Down). The answer is hidden below until you want it. Tuesday puzzles are a step up from Monday but still mostly straightforward.
Answer length: 4 squares
First letter
M _ _ _
First and last letters
M _ _ O
Show the answer
About the answer
MISO as a word: A thick paste made by fermentation of soybeans with the mold Aspergillus oryzae, used in making soups and sauces; (pharmacology, informal) Clipping of misoprostol. [(pharmacology) A drug used for various purposes including the prevention of drug-induced gastric ulcers an....
MISO has been an answer 4 times in the NYT Crossword and Mini since November 15, 2025.
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