This clue appeared in the NYT Crossword on Thursday, July 16, 2026 (53 Across). The answer is hidden below until you want it. Thursday puzzles often have a trick, such as a rebus (several letters in one square) or answers that bend the rules.
Answer length: 3 squares
First letter
P _ _
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About the answer
POX as a word: A disease characterized by purulent skin eruptions that may leave pockmarks; Syphilis.
POX has been an answer once in the NYT Crossword and Mini puzzles we have on file, which go back to October 23, 2025.
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