This clue appeared in the NYT Crossword on Monday, February 23, 2026 (10 Down). The answer is hidden below until you want it. Monday puzzles are the easiest of the week, so the clue is likely a plain definition.
Answer length: 3 squares
First letter
L _ _
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About the answer
LSD as a word: (organic chemistry) Abbreviation of lysergic acid diethylamide. [(organic chemistry) A powerful synthetic hallucinogen.]; Initialism of Lake Shore Drive (freeway in Chicago).
LSD has been an answer 13 times in the NYT Crossword and Mini since November 8, 2025.
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