This clue appeared in the NYT Crossword on Tuesday, July 21, 2026 (31 Across). The answer is hidden below until you want it. Tuesday puzzles are a step up from Monday but still mostly straightforward.
How to read this clue
This is a fill-in-the-blank clue: the answer completes the phrase, title or quotation.
Answer length: 5 squares
First letter
S _ _ _ _
First and last letters
S _ _ _ M
Show the answer
About the answer
SERUM as a word: Blood serum used as a blood product, in the practice of medicine: blood serum from the tissues of immunized animals (human or nonhuman), containing antibodie...; (skincare) A skincare product of varying consistencies with a high concentration of one or more active ingredients, for a targeted purpose, such as preventin....
SERUM has been an answer 4 times in the NYT Crossword and Mini since October 27, 2025.
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