This clue appeared in the NYT Crossword on Sunday, June 21, 2026 (84 Across). The answer is hidden below until you want it. Sunday puzzles are large (21 by 21) and themed, about as hard as a Wednesday or Thursday.
Answer length: 5 squares
First letter
A _ _ _ _
First and last letters
A _ _ _ N
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About the answer
ACTIN as a word: (biochemistry, uncountable) A globular structural protein that polymerizes in a helical fashion to form an actin filament (or microfilament); (biochemistry, countable) One of the six isoforms of actin.
ACTIN has been an answer 2 times in the NYT Crossword and Mini since May 1, 2026.
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